Prognostic Factors for Operated Gallbladder Cancer

Introduction: Gallbladder carcinoma (GBC) is one of the dismal gastrointestinal malignancies, with an unsatisfactory prognosis even after curative resection. There are several identified factors for GBC, though optimal prognostic predictive system has not been established. We aimed to determine significance recently proposed markers, such as Cancer Risk Score (GBRS) and Neutrophil-to-Lymphocyte Ratio (NLR), investigate ability a potential new index: (alkaline phosphatase (AP) + gamma-glutamyl transpeptidase)/lymphocyte ratio (AGLR). Method: Data from forty-two patients GBC who underwent surgery between 2013 2021 was reviewed retrospectively. Univariate multivariate analysis (Cox regression model) were performed associated overall survival (OS). Results: According univariate analysis, preoperative suspicion (p = 0.026), described lymphovascular invasion 0.027), high GBRS 0.028), AP (0.008) AGLR 0.036) prognosis. In contrast numerous literature, we do confirm influence NLR 0.564). Similarly, other trending ratios, Lymphocyte-to-Monocyte or Platelet-to-Lymphocyte Ratio, didn’t find 0.516 p 0.841, respectively). The indicated that 0.047) 0.046) independent OS. Conclusion: marker in GBC. Likewise, demonstrated good ability. Larger samples needed further validate these tools.